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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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5 / 65 resultslearn Stem Cell Factor
learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
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glaucoma medication with hair follicle stimulant effects
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extract, clone, and reinsert your own hair cells
Research
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research Scarring Hair Follicle Destruction Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses
Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
research Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research ISID1338 - Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
EGFR helps protect hair follicles from damage and scarring.
research Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
Community Join
5 / 1000+ resultscommunity How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"
Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.
community SCUBE3 and GT20029 could be the closet thing to a cure: Hair Follicle Regeneration and Protection Against DHT
SCUBE3 and GT20029 are potential treatments for hair loss, with SCUBE3 stimulating hair growth and GT20029 protecting against DHT. A combined approach using SCUBE3, finasteride or dutasteride, and later GT20029 could provide a comprehensive treatment for androgenetic alopecia.
community Testosterone in Reference Range Doesn't Cause Hair Loss
Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
community So...why does switching from fin to dut ruin people's hair?
Switching from finasteride to dutasteride can cause hair shedding, with mixed results; some see improvement, others see worsening. Using both treatments together initially may help reduce shedding.