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    GlossaryHair Follicle Destruction

    permanent damage to hair-producing skin structures

    Hair Follicle Destruction refers to the permanent damage or elimination of hair follicles, the tiny structures in the skin from which hair grows. This can occur due to various factors such as autoimmune conditions like alopecia areata, physical trauma, certain medical treatments like laser hair removal, or chronic inflammation. Once a hair follicle is destroyed, it cannot produce hair, leading to permanent hair loss in the affected area.

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      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

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      community Testosterone in Reference Range Doesn't Cause Hair Loss

      in Research/Science  51 upvotes 9 months ago
      Testosterone within the normal range does not significantly contribute to male pattern baldness (MPB); DHT is the main factor that can be controlled. Genetics play a crucial role in hair loss, and treatments like finasteride and dutasteride, which block DHT, can help despite potentially raising testosterone levels.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  933 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.