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    Glossary Hair Follicle Destruction

    permanent damage to hair-producing skin structures

    Hair Follicle Destruction refers to the permanent damage or elimination of hair follicles, the tiny structures in the skin from which hair grows. This can occur due to various factors such as autoimmune conditions like alopecia areata, physical trauma, certain medical treatments like laser hair removal, or chronic inflammation. Once a hair follicle is destroyed, it cannot produce hair, leading to permanent hair loss in the affected area.

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    1. Progressive and destructive hair follicle infections in a murine cutaneous anthrax model Microbial pathogenesis · 2007 · 2 citations
    2. Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege bioRxiv (Cold Spring Harbor Laboratory) · 2023
    3. Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses Journal of Investigative Dermatology · 1998 · 112 citations
    4. 1338 Epidermal growth factor receptor protects from immune privilege collapse and scarring hair follicle destruction 2023
    5. ISID1338 - Epidermal growth factor receptor protects from immune privilege collapse and scarring hair follicle destruction 2023
    6. The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    7. PRP: Alopecia Areata an Autoimmune Destruction of the Hair Journal of dermatology and dermatitis · 2018
    8. The walking dead: sequential nuclear and organelle destruction during hair development British Journal of Dermatology · 2017 · 16 citations
    9. The walking dead: sequential nuclear and organelle destruction during hair development British Journal of Dermatology · 2018
    10. Environmental and Cosmetic Factors in Hair Loss and Destruction Current problems in dermatology · 2007 · 12 citations
    11. Theoretical considerations in laser hair removal Dermatologic Clinics · 1999 · 150 citations
    12. Hair regrowth in cicatricial alopecia: A literature review The Journal of Dermatology · 2021 · 6 citations
    13. Extended theory of selective photothermolysis: A new recipe for hair cooking? Lasers in Surgery and Medicine · 2001 · 23 citations
    14. SOCS3 treatment prevents the development of alopecia areata by inhibiting CD8+ T cell-mediated autoimmune destruction Oncotarget · 2017 · 16 citations
    15. Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia? Clinical and Experimental Dermatology · 2009 · 39 citations
    16. Clinical Perspectives on Alopecia: From Hair Follicle Biology to Advanced Therapies International Journal of Drug Delivery Technology · 2026
    17. Alopecia areata Journal of The American Academy of Dermatology · 2017 · 290 citations
    18. Frontal fibrosing alopecia in postmenopausal women Journal of The American Academy of Dermatology · 2004 · 179 citations
    19. Permanent alopecia following chemotherapy and bone marrow transplantation Australasian Journal of Dermatology · 2000 · 63 citations
    20. Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options? Journal of dermatological science · 2016 · 56 citations
    21. Androgenetic alopecia in males: a histopathological and ultrastructural study Journal of Cosmetic Dermatology · 2009 · 42 citations
    22. Review of Scalp Alopecia due to a Clinically Unapparent or Minimally Apparent Neoplasm (SACUMAN) Acta dermato-venereologica · 2006 · 32 citations
    23. Report from the Cicatricial Alopecia Colloquium Journal of Investigative Dermatology · 2006 · 15 citations
    24. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    25. Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation Veterinary Pathology · 2012 · 5 citations
    26. Alopecia universalis successfully treated with tofacitinib Journal of the American Academy of Dermatology · 2017 · 2 citations
    27. Sterile neutrophilic dermatitis in a cat - a case report University of Zagreb University Computing Centre (SRCE) · 2008 · 2 citations
    28. Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases The Keio Journal of Medicine · 2022 · 1 citations
    29. Marketing research of medicinal products used for the treatment of primary cicatricial alopecia Farmatsevtychnyi zhurnal · 2026
    30. Clinical features of 109 patients with primary cicatricial alopecia: a 15-year retrospective study Acta Dermatovenerologica Alpina Pannonica et Adriatica · 2026