Morphological Characteristics of Epidermis and Dermis in Patients with Diffuse Alopecia, Androgenetic Alopecia, and Alopecia Areata

    April 2018 in “ Rossiiskii Zhurnal Kozhnykh i Venericheskikh Boleznei ”
    S. L. Kashutin, Колодин Д. Л, E. I. Tedder, Торшин В И, L. L. Shagrov, Шелыгин Борис Леонидович, N. A. Shutskiy, Шакирова Н. А, V. S Nekludova, Неклюдова В С, K. K Korolev, Кравченко С К, D. E Aristov, Аимбетова Г Е
    TLDR All types of alopecia involve hair follicle damage, especially in alopecia areata.
    The study investigated the morphological characteristics of the epidermis and dermis in 25 patients with different types of alopecia: androgenetic alopecia, alopecia areata, and diffuse alopecia. It found that all types were associated with hair follicle destruction, most notably in alopecia areata, due to lymphohistiocytic infiltrates and sclerotic changes in the dermis. Additionally, there was an increase in the thickness of the basal layer of the epidermis, indicating reduced mitotic activity of basal keratinocytes, especially in diffuse alopecia. Changes in the epidermis were secondary to dermal alterations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  932 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 1 year ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 6 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

    Related Research

    4 / 4 results