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autoimmune disorder causing patchy hair loss
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Neem Oil
natural substance from Neem tree with medicinal and pesticidal properties
learn Vitamin D
vitamin you should probably be taking for general health might also help your hair a little
learn Stem Cell Factor
Research
5 / 1000+ resultsresearch Eavesdropping on the Conversation Between Immune Cells and the Skin Epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Physiological Doses of Red Light Induce IL-4 Release in Cocultures Between Human Keratinocytes and Immune Cells
Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
research Skin-Resident Immune Cells Actively Coordinate Their Distribution With Epidermal Cells During Homeostasis
The study investigated how skin-resident immune cells, specifically Langerhans cells (LCs) and Dendritic Epidermal T cells (DETCs), coordinate their distribution with epithelial cells during homeostasis in live adult mice. It was found that LCs and DETCs maintain their positions despite the turnover of neighboring basal epithelial stem cells and explore basal epithelial cell junctions through dendritic extensions. Changes in epithelial cell density influenced immune cell density, indicating that epithelial cells determined immune tissue composition. LCs and DETCs were organized in a tiling pattern, which was actively maintained, and when removed, neighboring cells filled the spaces to re-establish this pattern. The GTPase Rac1 was necessary for LCs to maintain their positional stability and tiling pattern. These findings suggested that epidermal cells regulated immune cell density, and immune cells maintained a non-random spatial distribution, enhancing the epidermis's response to environmental challenges.
research UVB-Induced Depletion of Donor-Derived Dendritic Cells Prevents Allograft Rejection of Immune-Privileged Hair Follicles in Humanized Mice
UV light helped human hair transplants survive in mice without broad immunosuppression.
research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
Community Join
5 / 325 resultscommunity Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people
Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.
community Does RU58841 potentially cause cancer?
RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.
community If PP405 goes systemic this would be quite catastrophic
Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.
community Boys how is no one seeing positive results from pyrilutamide
Pyrilutimide, a treatment for hair loss; it's effectiveness compared to other treatments such as Finasteride and RU58841; and some users’ experiences with the treatment.
community "Hair Follicle Stem Cells are quiescent 99% of the time and permanently reside in the hair follicle"
Hair follicles are mostly dormant but can be reactivated with treatments like minoxidil, finasteride, and microneedling. A new drug, PP405, shows promise for hair regrowth but may not be available until 2027-2028.