Search

for
Search:

Glossary Neutrophils

white blood cells that engulf and destroy pathogens

Neutrophils, also known as polymorphonuclear leukocytes (PMNs), are a type of white blood cell that plays a crucial role in the body's immune response. They are the first responders to sites of infection, where they engulf and destroy pathogens through a process called phagocytosis. Neutrophils are characterized by their multi-lobed nuclei and granular cytoplasm, which contains enzymes that help break down invading microbes.

Related Terms

Research

5 / 1000+ results

research CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17

32 citations , January 2024 in “The Journal of Experimental Medicine”

This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.

research Expression of Neutrophil Gelatinase-Associated Lipocalin in Calcium-Induced Keratinocyte Differentiation

20 citations , January 2008 in “Journal of Korean Medical Science”

This study found that NGAL expression increased in calcium-induced keratinocyte differentiation in vitro and was highly elevated in psoriasis-like skin conditions and skin cancers, suggesting a role in skin hyperplasia and homeostasis.

research REVIEW OF SO-CALLED ASEPTIC NEUTROPHILIC DERMATOSES

17 citations , August 1983 in “Australasian Journal of Dermatology”

The review says skin conditions with sterile pustules need more research for better treatments.

research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils

16 citations , September 2020 in “British journal of dermatology/British journal of dermatology, Supplement”

This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.

research Inflammatory memory-activated biomimetic nanovesicles regulate neutrophil plasticity and metabolic reprogramming for rapid diabetic wound healing via targeting miR-193a-5p/TLR4/JNK/P38 MAPK pathways

9 citations , February 2025 in “Journal of Nanobiotechnology”

In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.

View more "neutrophils" in research →

Learn

— no results

Community Join

— no results

Try a deeper search in community →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →