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Glossary Neutrophilic

involves increased activity of infection-fighting white blood cells

Neutrophilic refers to the presence or activity of neutrophils, which are a type of white blood cell crucial for fighting infections. In medical contexts, it often describes conditions or responses where there is an increased number of neutrophils, such as in inflammation or infection. For example, a neutrophilic response in the skin might indicate an underlying bacterial infection or an inflammatory condition.

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research CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17

32 citations , January 2024 in “The Journal of Experimental Medicine”

This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.

research Erosive pustular dermatosis of the scalp: A neutrophilic folliculitis within the spectrum of neutrophilic dermatoses

25 citations , October 2018 in “Journal of The American Academy of Dermatology”

This study concluded that erosive pustular dermatosis of the scalp may be a type of spongiotic, pustular superficial folliculitis, sharing similarities with other neutrophilic dermatoses.

research REVIEW OF SO-CALLED ASEPTIC NEUTROPHILIC DERMATOSES

17 citations , August 1983 in “Australasian Journal of Dermatology”

The review says skin conditions with sterile pustules need more research for better treatments.

research Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils

16 citations , September 2020 in “British journal of dermatology/British journal of dermatology, Supplement”

This review explores the role of neutrophil recruitment in the inflammation seen in hidradenitis suppurativa and emphasizes potential therapeutic targets within these pathways, but it reports no new clinical results.

research Neutrophil extracellular traps impair regeneration

4 citations , October 2021 in “Journal of Cellular and Molecular Medicine”

This study observed that mature neutrophils and their extracellular traps inhibit wound-induced hair follicle neogenesis in mice, despite being stimulated by pro-regenerative cues.

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