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GlossaryNeutrophil Recruitment

process where white blood cells move to infection sites

Neutrophil recruitment is the process by which neutrophils, a type of white blood cell, are directed to move from the bloodstream to the site of an infection or injury. This is a crucial part of the body's immune response, as neutrophils help to fight off pathogens by engulfing and destroying them.

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research Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

22 citations, December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology”

A mouse gene mutation increases the risk of skin cancer.

research When Bugs and Drugs Conspire: Driving Acneiform Skin Toxicity

1 citations, February 2020 in “The Journal of clinical investigation/The journal of clinical investigation”

Certain cancer drugs interact with skin bacteria to cause acne-like rashes.

The Spectrum of PLEC Sequence Variants and Related Plectinopathies Including Novel Association with Epidermolysis Bullosa Pruriginosa

research The Spectrum of PLEC Sequence Variants and Related Plectinopathies Including Novel Association with Epidermolysis Bullosa Pruriginosa

November 2022 in “Journal of Investigative Dermatology”

Neutrophils quickly respond to skin injury.

research Proteomic Evaluation of Four Botanical Extracts on Skin Cells

September 2019 in “Journal of Investigative Dermatology”

Four botanical extracts were found to quickly attract neutrophils to wounded skin in zebrafish.

Transgenic Mice Overexpressing CD109 in the Epidermis Display Decreased Inflammation and Granulation Tissue and Improved Collagen Architecture During Wound Healing

research Transgenic Mice Overexpressing CD109 in the Epidermis Display Decreased Inflammation and Granulation Tissue and Improved Collagen Architecture During Wound Healing

22 citations, February 2013 in “Wound Repair and Regeneration”

Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.