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    Glossary Neutrophil Extracellular Traps

    web-like structures released by white blood cells to trap pathogens

    Neutrophil Extracellular Traps (NETs) are web-like structures composed of DNA, histones, and antimicrobial proteins that are released by neutrophils, a type of white blood cell, to trap and kill pathogens. This process, known as NETosis, helps the immune system control infections but can also contribute to inflammation and tissue damage if not regulated properly.

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    1. Neutrophil extracellular traps impair regeneration Journal of Cellular and Molecular Medicine · 2021 · 4 citations
    2. Neutrophil extracellular traps impair regeneration bioRxiv (Cold Spring Harbor Laboratory) · 2020
    3. 461: THE PROFIBROGENIC ROLE OF NEUTROPHIL EXTRACELLULAR TRAPS IN STENOTIC CROHN'S DISEASE: A NEW ANTIFIBROTIC TARGET? Gastroenterology · 2022
    4. Identification and single-cell analysis of prognostic genes related to mitochondrial and neutrophil extracellular traps in bladder cancer Scientific Reports · 2025
    5. Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling Seminars in cell & developmental biology · 2022 · 5 citations
    6. 523 Targeting NETosis to treat delayed wound healing in a humanized mouse model of sickle cell disease Journal of Investigative Dermatology · 2024
    7. 603 Degradation of aberrant NETs by DNases is a promising therapeutic strategy for SJS/TEN Journal of Investigative Dermatology · 2023
    8. 1431 Neutralizing α-toxin accelerates healing of Staphylococcus aureus-infected wounds in normal and diabetic mice Journal of Investigative Dermatology · 2018
    9. Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration Nature Communications · 2023
    10. The crosstalk of monocyte-neutrophil in hair follicles regulates neutrophil transepidermal migration in contact dermatitis Communications Biology · 2025 · 6 citations
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