Review of Aseptic Neutrophilic Dermatoses

In the 1983 review, Samuel L. Moschella discussed various neutrophilic dermatoses, which are skin conditions characterized by sterile pustules or cellulitis-like lesions with tissue neutrophilia, sometimes accompanied by leucocytosis and fever. The review classified and described several dermatoses, including pustular psoriasis, subcorneal pustular dermatosis, Sweet's syndrome, Behcet's syndrome, familial Mediterranean fever, pyoderma gangrenosum, and others. It highlighted the lack of predictably effective therapies and the need for further research. Specific conditions such as persistent palmoplantar pustulosis, acrodermatitis continua of Hallopeau, generalized pustular psoriasis, Reiter's syndrome, bowel bypass syndrome, and infantile acropustulosis were detailed, with notes on their characteristics, demographics, and treatment responses. The review emphasized the complexity of these conditions, the variability in treatment efficacy, and the importance of continued investigation into their etiologies and management.