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GlossaryNeutrophilic Dermatosis

group of skin disorders with excess neutrophils causing lesions

Neutrophilic dermatosis is a group of skin disorders characterized by the accumulation of neutrophils, a type of white blood cell, in the skin. These conditions often present with red, swollen, and sometimes painful lesions or pustules, and can be associated with systemic diseases like inflammatory bowel disease or certain types of leukemia.

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research Erosive Pustular Dermatosis of the Scalp: A Neutrophilic Folliculitis Within the Spectrum of Neutrophilic Dermatoses

25 citations, October 2018 in “Journal of The American Academy of Dermatology”

Erosive pustular dermatosis of the scalp is a type of skin inflammation often confused with other conditions, requiring continuous treatment.

research Review of Aseptic Neutrophilic Dermatoses

17 citations, August 1983 in “Australasian Journal of Dermatology”

The review says skin conditions with sterile pustules need more research for better treatments.

research The Many Faces of Interleukin-17 in Inflammatory Skin Diseases

77 citations, April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

IL-17 is a key target for treating inflammatory skin diseases, especially psoriasis.

research Follicular Neutrophilic Inflammation in Hidradenitis Suppurativa

January 2018 in “Springer eBooks”

Hidradenitis Suppurativa is likely an autoinflammatory disease, and better understanding its causes could improve treatments.

research Mucocutaneous Reactions to Chemotherapy

275 citations, March 1999 in “Journal of The American Academy of Dermatology”

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.