Sweet Syndrome: An Unusual Presentation of Chronic Granulomatous Disease in a Child

This case study described a 2-year-old African-American male initially diagnosed with Sweet syndrome, which is rare in children, and later found to have chronic granulomatous disease (CGD). The child presented with patchy alopecia and a pustular rash that did not respond well to initial treatments. Laboratory tests and a biopsy revealed unusual results, leading to the diagnosis of CGD, a rare inherited disorder affecting phagocytic cell function. The patient improved with dapsone and prednisone, showing no relapse after tapering off the medication. This case highlighted the unusual presentation of CGD as Sweet syndrome and emphasized the need for high clinical suspicion and appropriate testing in similar cases.