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GlossaryMononuclear Cells

white blood cells with a single round nucleus

Mononuclear cells, also known as mononuclear leukocytes or MNCs, are a type of white blood cell characterized by having a single round nucleus. These cells include lymphocytes and monocytes, which play crucial roles in the immune system by fighting infections and aiding in immune responses.

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Hallmark Evidence of Lipopolysaccharide Tolerance in Obese Women with Polycystic Ovary Syndrome: LPS-Induced NFkB Suppression in Mononuclear Cells Linked to Hyperandrogenism

research Hallmark Evidence of Lipopolysaccharide Tolerance in Obese Women with Polycystic Ovary Syndrome: LPS-Induced NFkB Suppression in Mononuclear Cells Linked to Hyperandrogenism

September 2018 in “Fertility and Sterility”

High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.

Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy

research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy

4 citations, July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.

research Subset Analysis of NKG2D+ Cells in Peripheral Blood Mononuclear Cells

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study suggests that a specific type of immune cell, memory-like NK cells, may increase during active hair loss in Alopecia areata.

Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata

research Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata

1 citations, October 2022 in “International Journal of Molecular Sciences”

Using healthy donor stem cells can potentially calm overactive immune cells and reduce inflammation in severe hair loss patients, offering a possible treatment method.

research Availability of mRNA from Peripheral Blood Mononuclear Cells for Mutational Analysis in Dystrophic Epidermolysis Bullosa

November 2022 in “Journal of Investigative Dermatology”

Scientists developed a new way to study mutations in a skin condition using blood cells, which may help diagnose and treat the disease.

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