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    Glossary Mononuclear Cells

    white blood cells with a single round nucleus

    Mononuclear cells, also known as mononuclear leukocytes or MNCs, are a type of white blood cell characterized by having a single round nucleus. These cells include lymphocytes and monocytes, which play crucial roles in the immune system by fighting infections and aiding in immune responses.

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    Research 30 of 1000+

    1. Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS Fertility and Sterility · 2018
    2. Impaired responses of peripheral blood mononuclear cells to T-cell stimulants in alopecia areata patients with a poor response to topical immunotherapy 2008 · 4 citations
    3. Uncontrolled Clinical Trial of Quality- and Quantity-cultured Peripheral Blood Mononuclear Cell Treatment for Androgenic Alopecia Plastic & Reconstructive Surgery · 2025
    4. 058 Subset analysis of NKG2D+ cells in peripheral blood mononuclear cells 2023
    5. Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata BBA clinical · 2016 · 12 citations
    6. Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells of a Healthy Donor on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata: Targeting Dysregulated T Cells and the Acquisition of Immunotolerance International Journal of Molecular Sciences · 2022 · 1 citations
    7. 302 Availability of mRNA Obtained from Peripheral Blood Mononuclear Cells for Mutational Analysis in Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2022
    8. Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata British Journal of Dermatology · 2011 · 48 citations
    9. The Secretome of Irradiated Peripheral Mononuclear Cells Attenuates Hypertrophic Skin Scarring Pharmaceutics · 2023 · 1 citations
    10. TO IDENTIFY THE EXPRESSION OF INTRACELLULAR TOLL-LIKE RECEPTORS (TLRS) IN PERIPHERAL BLOOD MONONUCLEAR CELLS OF ALOPECIA AREATA 2023
    11. Role of Cytotoxic T Cells in Chronic Alopecia Areata Journal of Investigative Dermatology · 2000 · 127 citations
    12. Hair regrowth in alopecia areata patients following Stem Cell Educator therapy BMC medicine · 2015 · 55 citations
    13. The effect of mesenchymal stem cell-conditioned medium gel on burn wound healing in rat 2022 · 3 citations
    14. Oral syphilis: report of three cases and characterization of the inflammatory cells Annals of diagnostic pathology · 2015 · 32 citations
    15. Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata Research Square (Research Square) · 2023
    16. scMC learns biological variation through the alignment of multiple single-cell genomics datasets Genome biology · 2021 · 822 citations
    17. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    18. Stem cell therapy as a novel therapeutic intervention for resistant cases of alopecia areata and androgenetic alopecia Journal of Dermatological Treatment · 2016 · 39 citations
    19. iNKT cells ameliorate human autoimmunity: Lessons from alopecia areata Journal of autoimmunity · 2018 · 27 citations
    20. Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome Stem Cell Research & Therapy · 2025 · 1 citations
    21. Table 1_Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata.docx Figshare · 2025
    22. 164 Epigenetic and transcriptional profiling of PBMCs in mild and severe alopecia areata using single-cell RNA-Seq and ATAC-Seq Journal of Investigative Dermatology · 2023
    23. 165 Single-cell RNA sequencing analysis unveils highly active yet diminished CD14+CD16- circulating monocytes, independent of alopecia areata severity Journal of Investigative Dermatology · 2023
    24. 586 Increase in CD8+ effector memory cells re-expressing CD45RA (TEMRA) reflects disease activity and enables early prediction of therapeutic outcome in rapidly progressive alopecia areata Journal of Investigative Dermatology · 2023
    25. 004 Cell-based therapy may be effective in alopecia areata: Preclinical evidence that autologous, peripheral regulatory γdT cells are preventive in human ex vivo and therapeutic in human in vivo models Journal of Investigative Dermatology · 2022
    26. Application of genetically modified umbilical cord blood cells and direct gene therapy for treatment of skin wounds in rats Genes and Cells · 2014
    27. Acute diffuse and total alopecia: A new subtype of alopecia areata with a favorable prognosis Journal of The American Academy of Dermatology · 2008 · 64 citations
    28. Demodex Folliculitis of the Scalp: Clinicopathological Study of an Uncommon Entity The American Journal of Dermatopathology · 2016 · 15 citations
    29. The Role of Platelet-Rich Plasma in the Prevention of Chemotherapy-Induced Alopecia Skin appendage disorders · 2019 · 2 citations
    30. Diffuse Alopecia Areata 2018 · 2 citations