Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus the Humanized AA Mouse Model
April 2019
in “
Journal of Investigative Dermatology
”
New to Alopecia Areata? There is a guide in the encyclopedia. Read the guide → alopecia areata C3H/HeJ mice humanized AA mouse model psychoemotional stressors IFN-γ histological features immunoinhibitory agents human scalp skin xenotransplantation SCID mice IL-2-stimulated PBMCs CD8+ T cells NKG2D+ cells unconventional T cell subtypes interferon gamma severe combined immunodeficiency mice peripheral blood mononuclear cells cytotoxic T cells
Studysummary This paper discusses two preclinical models for studying alopecia areata and finds that testing new therapeutic agents should involve both the C3H/HeJ mouse model and the humanized mouse model for comprehensive insights.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
