Mouse Models of Alopecia Areata: C3H/HeJ Mice Versus the Humanized AA Mouse Model
April 2019
in “
Journal of Investigative Dermatology
”
alopecia areata C3H/HeJ mice humanized AA mouse model psychoemotional stressors IFN-γ histological features immunoinhibitory agents human scalp skin xenotransplantation SCID mice IL-2-stimulated PBMCs CD8+ T cells NKG2D+ cells unconventional T cell subtypes interferon gamma severe combined immunodeficiency mice peripheral blood mononuclear cells cytotoxic T cells
Studysummary This paper discusses two preclinical models for studying alopecia areata and finds that testing new therapeutic agents should involve both the C3H/HeJ mouse model and the humanized mouse model for comprehensive insights.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
Read the full study on jidonline.org →