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GlossaryNKG2D+ cells

immune cells with receptors targeting stressed or abnormal cells

NKG2D+ cells are immune cells that have a receptor called NKG2D on their surface. This receptor helps them recognize and destroy stressed or abnormal cells, such as those infected by viruses or transformed into cancer cells. These cells play a crucial role in the body's defense mechanisms, particularly in identifying and eliminating potential threats.

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research Subset Analysis of NKG2D+ Cells in Peripheral Blood Mononuclear Cells

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study suggests that a specific type of immune cell, memory-like NK cells, may increase during active hair loss in Alopecia areata.

research Innate Lymphoid Cells Type 1 May Be New, Non-Antigen-Specific Player in the Pathogenesis of Alopecia Areata

August 2019

Innate lymphoid cells type 1 may contribute to alopecia areata by damaging hair follicles.

research An Immune Regulatory CCT Repeat Containing Oligodeoxynucleotide Capable of Causing Hair Loss in Male Mice

January 2016 in “Human & Experimental Toxicology”

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

research Editor's Evaluation: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata

September 2022

ILC1-like cells can independently cause alopecia areata by affecting hair follicles.

research Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata

June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

ILC1-like cells can cause alopecia areata by attacking hair follicles.

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