Mathematical Model for Alopecia Areata

June 2015 in “ Journal of theoretical biology ”

A Dobréva, Ralf Paus, N. G. Cogan

alopecia areata immune privilege interferon-γ effector autoreactive CD4+ T-cells effector autoreactive CD8+ T-cells NKG2D+ cells AA IFN-γ

Studysummary This study suggests that immune privilege guardians and the pro-inflammatory cytokine interferon-γ significantly influence the dynamics of alopecia areata, supporting the hypothesis that immune privilege collapse is crucial in its development.

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