The Immunopathobiology of Lichen Planopilaris

    December 2011 in “ [Thesis]. Manchester, UK: The University of Manchester; 2011. ”
    Matthew Harries
    TLDR Immune system failure in hair follicles causes lichen planopilaris, leading to hair loss.
    Lichen planopilaris (LPP) was described as a form of scarring alopecia characterized by inflammation and destruction of hair follicles. The study explored the immunopathobiology of LPP, focusing on the role of immune cells and cytokines in the disease process. It highlighted that T cells, particularly CD8+ T cells, were implicated in the pathogenesis of LPP, contributing to follicular damage. The research suggested that targeting specific immune pathways could offer potential therapeutic strategies for managing LPP. However, the study emphasized the need for further research to fully understand the complex immune mechanisms involved in LPP.
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      in Research  830 upvotes 1 year ago
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