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GlossaryLichen Planopilaris (LPP)

rare inflammatory condition causing scarring and permanent hair loss

Lichen Planopilaris (LPP) is a rare inflammatory condition that affects the hair follicles, leading to scarring and permanent hair loss. It is a form of lichen planus that specifically targets the scalp, causing symptoms such as redness, itching, and scaling. Early diagnosis and treatment are crucial to prevent extensive hair loss.

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research Prevalence of Hormonal and Endocrine Dysfunction in Patients with Lichen Planopilaris: A Retrospective Data Analysis of 168 Patients

44 citations, February 2017 in “Journal of the American Academy of Dermatology”

Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.

Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

research Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

4 citations, November 2016 in “Journal of Cutaneous Pathology”

Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.

research Lichen Planus Pigmentosus and Lichen Planus Pigmentosus: 35 Cases in Armenia, Colombia

1 citations, May 2015 in “Journal of The American Academy of Dermatology”

Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.

research Evaluation of Hair Surface Structure and Morphology of Patients with Lichen Planopilaris by Atomic Force Microscopy

September 2024 in “Skin Research and Technology”

AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.

research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations, April 2006 in “International Journal of Dermatology”

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 6 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Anyone with LPP have regrowth with Xeljanz?

in Treatment 3 upvotes 7 months ago

The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.

community Losing Hair on Dutasteride? You might have LPP

in Research/Science 97 upvotes 2 weeks ago

Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

in Research/Science 128 upvotes 6 days ago

Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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