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GlossaryLichen Planopilaris (LPP)

rare inflammatory condition causing scarring and permanent hair loss

Lichen Planopilaris (LPP) is a rare inflammatory condition that affects the hair follicles, leading to scarring and permanent hair loss. It is a form of lichen planus that specifically targets the scalp, causing symptoms such as redness, itching, and scaling. Early diagnosis and treatment are crucial to prevent extensive hair loss.

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research Prevalence of Hormonal and Endocrine Dysfunction in Patients with Lichen Planopilaris: A Retrospective Data Analysis of 168 Patients

44 citations, February 2017 in “Journal of the American Academy of Dermatology”

Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.

Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

research Reply to ‘CD123 Immunohistochemistry for Plasmacytoid Dendritic Cells Is Useful in the Diagnosis of Scarring Alopecia’: Three PDC-Related Parameters Are Useful in Differentiating Lupus Alopecia from LPP

4 citations, November 2016 in “Journal of Cutaneous Pathology”

Three characteristics of plasmacytoid dendritic cells help tell apart lupus-related hair loss from LPP.

research Lichen Planus Pigmentosus and Lichen Planus Pigmentosus: 35 Cases in Armenia, Colombia

1 citations, May 2015 in “Journal of The American Academy of Dermatology”

Lichen planus pigmentosus and fibrosing frontal alopecia in Colombia are likely different stages of the same disease.

research Evaluation of Hair Surface Structure and Morphology of Patients with Lichen Planopilaris by Atomic Force Microscopy

September 2024 in “Skin Research and Technology”

AFM can help diagnose lichen planopilaris by identifying specific hair structure changes.

research Frontal Fibrosing Alopecia Versus Lichen Planopilaris: A Clinicopathological Study

126 citations, April 2006 in “International Journal of Dermatology”

The conclusion is that FFA and LPP have similar scalp biopsy features, making them hard to distinguish histologically, and FFA may be a specific kind of scarring hair loss.

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community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community Anyone with LPP have regrowth with Xeljanz?

in Treatment 2 upvotes 3 months ago

The conversation is about using Xeljanz for hair regrowth in individuals with LPP. The user is seeking experiences and expectations from others who have tried this treatment.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Anger and frustration as I finally learn my diagnosis.

in Female 6 upvotes 1 year ago

A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

community Turning vellus hairs into terminal hair

in Research/Science 12 upvotes 1 month ago

People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

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