L-Proline
Research
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research L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes
This study found that a combination of oral compounds improved metabolic activity, cell viability, and proliferation in hair follicular keratinocytes, with L-cystine playing a key role in protection against oxidative stress.
research A Mixture of Tocopherol Acetate and L-Menthol Synergistically Promotes Hair Growth in C57BL/6 Mice
In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.
research The Prostaglandin Synthases, COX-2 and L-PGDS, Mediate Prostate Hyperplasia Induced by Low-Dose Bisphenol A
In this study, low-dose BPA was associated with induced prostatic hyperplasia in rats, potentially mediated by COX-2 and L-PGDS through pathways involving cell proliferation and apoptosis.
research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?
This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.
research The Human Cysteine Protease Cathepsin V Can Compensate for Murine Cathepsin L in Mouse Epidermis and Hair Follicles
Human cathepsin V can replace mouse cathepsin L to maintain normal skin and hair in mice.
research L-Carnitine-L-Tartrate Promotes Human Hair Growth In Vitro
This study found that l-carnitine stimulated hair growth in vitro by promoting proliferation and reducing apoptosis in human scalp hair follicles, suggesting potential as a treatment for hair loss.
research Improvement of Androgenetic Alopecia with Topical Sophora Flavescens Aiton Extract, and Identification of the Two Active Compounds in the Extract That Stimulate Proliferation of Human Hair Keratinocytes
This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.
research Hair Growth Promoting Effect of Urtica Dioica L
This study found that Urticadioica L ethanol extracts enhanced hair growth and reduced catagen transition in human hair follicles in an ex vivo organ culture model.
research The Lysosomal Protease Cathepsin L Is an Important Regulator of Keratinocyte and Melanocyte Differentiation During Hair Follicle Morphogenesis and Cycling
This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.
research Evaluation of the Effect of Plant Mixture Ethanol Extracts Containing Biota Orientalis L. Extract on Suppression of Sebum in Cultured Sebocytes and on Stimulation of Growth of Keratinocytes Co-cultured with Hair Papilla Cells
This study observed that Biota orientalis L. leaf extract may promote hair growth and suppress sebum production in human cells, suggesting potential benefits for hair restoration.
research Periplaneta Americana Extract Promotes Hair Regrowth in Alopecia Areata Mice by Reducing Inflammation and Modulating Skin Microbiota
In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.
research Autologous Skin Transplantation Using Water Extract of Bay Leaves (Laurus Nobilis L.)
This study found that applying aqueous bay leaf extract to skin graft wounds in rabbits reduced inflammation and improved tissue regeneration, leading to enhanced healing compared to untreated controls, particularly in terms of collagen organization, fibrosis, and inflammation modulation over a 21-day period.
research Expression of Bioactive Recombinant Human Fibroblast Growth Factor 10 in Carthamus Tinctorius L. Seeds
This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
research Utilization of Nutgrass Extract (Cyperus Rotundus L.) as a Natural Ingredient for Hair Growth: Literature Review
This literature review suggests that Cyperus rotundus L extract shows promise as a natural hair growth agent due to its bioactive compounds and mechanisms that stimulate hair growth, although more human clinical trials are needed to confirm its safety and efficacy.
research Periplaneta Americana Extract Promotes Hair Regrowth in Alopecia Areata Mice by Reducing Inflammation and Modulating Skin Microbiota
In this study, PA-011 extract was reported to promote hair growth and alleviate alopecia areata symptoms in mice by reducing skin inflammation and modulating skin microbiota.
research The Extract of Periplaneta Americana Promotes Hair Regrowth in Mice with Alopecia by Regulating the FOXO/PI3K/AKT Signaling Pathway and Skin Microbiota
This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
research Production and Biological Activities of Oligo Pectin from Early Immature Fruit of Durio Zibethinus L.
This study identified pectin in early immature durian fruits and found that pectin-oligosaccharides derived from them show stronger antioxidant and antiglycation activities, with potential applications in cosmetic products.
research Amino Acids Oral Treatment for the Amelioration of Skin, Hair, and Nails Conditions: An Open-Label Study
This study found that a food supplement improved skin moisturization, elasticity, and thickness, reduced telogen hair density, and enhanced nail status in women with mild-to-moderate aging signs after 84 days.
research Untargeted Metabolomics Analysis of Plasma Metabolic Characteristics in Patients With Acne and Insulin Resistance
This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.
research Xenobiotics In Vitro: The Influence of L-Cystine, Pantothenate, and Miliacin on Metabolic and Proliferative Capacity of Keratinocytes
This study found that L-cystine, D-pantothenat, and miliacin can enhance the metabolic capacity and proliferation of human keratinocytes, with a combination of these additives potentially providing synergistic benefits in growth media.