Two Hydroxyproline Galactosyltransferases, GALT5 and GALT2, Function in Arabinogalactan-Protein Glycosylation, Growth, and Development in Arabidopsis

    May 2015 in “ PloS one ”
    Debarati Basu, Wuda Wang, Sheng Ma, Taylor DeBrosse, Emily Poirier, Kirk Emch, Eric Soukup, Lü Tian, Allan M. Showalter
    TLDR GALT5 and GALT2 are important for plant growth and development because they help with protein glycosylation.
    The study investigated the roles of two hydroxyproline galactosyltransferases, GALT5 and GALT2, in the glycosylation of arabinogalactan-proteins (AGPs) in Arabidopsis. It was found that these enzymes were crucial for proper AGP glycosylation, which in turn was essential for normal plant growth and development. Mutants lacking these enzymes exhibited significant developmental defects, including issues with root and shoot growth, delayed flowering, and increased sensitivity to salt stress, highlighting the importance of AGP glycosylation in plant biology.
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