O-Glycosylated Cell Wall Proteins Are Essential in Root Hair Growth

June 2011 in “ Science ”

Silvia M. Velasquez, Martiniano M. Ricardi, Javier Gloazzo Dorosz, Paula Virginia Fernández, Alejandro D. Nadra, Laércio Pol-Fachin, Jack Egelund, Sascha Gille, Jesper Harholt, Marina Ciancia, Hugo Verli, Markus Pauly, Antony Bacic, Carl Erik Olsen, Peter Ulvskov, Bent Larsen Petersen, Chris Somerville, Norberto D. Iusem, José M. Estevez

O-glycosylated cell wall proteins hydroxyproline-rich glycoproteins HRGPs extensins EXTs prolyl 4-hydroxylases P4Hs arabinosyltransferases arabinosylation cell-wall self-assembly root hair elongation

TLDR Proteins with added sugars are crucial for plant root hair growth.

The study concluded that O-glycosylated cell wall proteins, specifically hydroxyproline-rich glycoproteins (HRGPs) like extensins (EXTs), were essential for root hair growth in Arabidopsis thaliana. Disruption of prolyl 4-hydroxylases (P4Hs) or arabinosyltransferases blocked polarized growth in root hairs and reduced arabinosylation of EXTs, indicating that proper O-glycosylation was crucial for cell-wall self-assembly and root hair elongation. The research involved various techniques, including confocal microscopy and molecular modeling, and highlighted the importance of these glycoproteins in nutrient absorption and plant health.

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