A Small Multigene Hydroxyproline-O-Galactosyltransferase Family Functions in Arabinogalactan-Protein Glycosylation, Growth, and Development in Arabidopsis

    December 2015 in “ BMC plant biology
    Debarati Basu, Lü Tian, Wuda Wang, Shauni Bobbs, Hayley Herock, Andrew Travers, Allan M. Showalter
    TLDR Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.
    The study investigated the role of a small multigene family of hydroxyproline-O-galactosyltransferases (HPGTs) in the glycosylation of arabinogalactan-proteins (AGPs) and their impact on growth and development in Arabidopsis. Researchers identified and characterized several HPGT genes, showing their involvement in adding galactose to AGPs. Mutant plants with disrupted HPGT genes exhibited altered AGP glycosylation, leading to defects in root and shoot growth, seed set, pollen tube growth, and leaf senescence. The findings highlighted the importance of HPGT-mediated glycosylation in the proper functioning of AGPs and normal plant development.
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