Cell Fate Decisions: Emerging Roles for Metabolic Signals and Cell Morphology

    November 2017 in “ EMBO Reports ”
    Sumitra Tatapudy, Francesca M. Aloisio, Diane L. Barber, Todd Nystul
    Studysummary This review discusses the roles of metabolism, reactive oxygen species, intracellular pH, and cell morphology in influencing cell fate decisions during stem cell differentiation but reports no new experimental results.
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    Research cited in this study 4

    1. Lactate Dehydrogenase Activity Drives Hair Follicle Stem Cell Activation Nature cell biology · 2017
    2. Epigenetic Control of Adult Stem Cell Function Nature Reviews Molecular Cell Biology · 2016
    3. Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche Cell stem cell · 2011
    4. Deregulated Expression of c-Myc Depletes Epidermal Stem Cells Nature Genetics · 2001