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    GlossaryGlycolysis

    metabolic pathway breaking down glucose into energy and pyruvate

    Glycolysis is a metabolic pathway that breaks down glucose, a type of sugar, into pyruvate, producing energy in the form of ATP (adenosine triphosphate). This process occurs in the cytoplasm of cells and is the first step in both aerobic and anaerobic respiration, making it essential for energy production in almost all living organisms.

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      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 2 weeks ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community The mechanism of androgenic alopecia

      in Research/Science  31 upvotes 3 weeks ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community Can we get a reality check on PP405?

      in Research/Science  79 upvotes 1 week ago
      PP405 is a promising hair loss treatment that may outperform minoxidil and finasteride by reviving dormant follicles and promoting significant regrowth. Results from ongoing trials are awaited, with a potential market release between 2028-2030.

      community If PP405 goes systemic this would be quite catastrophic

      in Research/Science  4 upvotes 9 months ago
      Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.