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    Glossary Glycolysis

    metabolic pathway breaking down glucose into energy and pyruvate

    Glycolysis is a metabolic pathway that breaks down glucose, a type of sugar, into pyruvate, producing energy in the form of ATP (adenosine triphosphate). This process occurs in the cytoplasm of cells and is the first step in both aerobic and anaerobic respiration, making it essential for energy production in almost all living organisms.

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    Research 30 of 649

    1. Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling Pharmaceutics · 2023 · 10 citations
    2. Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome Drug Design Development and Therapy · 2025 · 3 citations
    3. Multi-omics identifies L-rhamnose as a metabolic regulator that enhances glycolysis to promote hair follicle growth Phytomedicine · 2025
    4. Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis 2024
    5. Additional file 1 of Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis Figshare · 2024
    6. Autophagy induces hair follicle stem cell activation and hair follicle regeneration by regulating glycolysis Research Square (Research Square) · 2023
    7. ISID1394 - Long non-coding RNA AL136131.3 inhibits hair growth through mediating glycolysis in androgenetic alopecia 2023
    8. 1328 HIF1A stabilisation in the human hair follicle promotes glycolysis Journal of Investigative Dermatology · 2018
    9. 1394 Long non-coding RNA AL136131.3 inhibits hair growth through mediating glycolysis in androgenetic alopecia Journal of Investigative Dermatology · 2023
    10. <i>PIK3CA</i> gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect Proceedings of the National Academy of Sciences · 2025
    11. 899 HIF1A stabilisation in the ORS of human hair follicles promotes aerobic glycolysis and synthesis of angiogenic factors Journal of Investigative Dermatology · 2019
    12. Phosphofructokinase (Pfk) Regulation of Glycolysis in Skin Journal of Investigative Dermatology · 1971 · 19 citations
    13. μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism Current Research in Physiology · 2021 · 4 citations
    14. Extracellular vesicle-derived lncRNA VIM-AS1 promotes diabetic wound healing by promoting glycolysis and alleviating cellular senescence Stem Cell Research & Therapy · 2025 · 3 citations
    15. [Studies on enzyme activities in the hair root in male pattern baldness: glycolytic enzyme, acid hydrolase, transglutaminase and ornithine decarboxylase activities of plucked hair roots]. PubMed · 1985
    16. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993 · 71 citations
    17. Lactate dehydrogenase activity drives hair follicle stem cell activation Nature cell biology · 2017 · 202 citations
    18. Azithromycin and Roxithromycin define a new family of “senolytic” drugs that target senescent human fibroblasts Aging · 2018 · 133 citations
    19. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    20. Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin Nature communications · 2019 · 36 citations
    21. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming Experimental and Molecular Medicine · 2018 · 19 citations
    22. Metabolic Teamwork in the Stem Cell Niche Cell metabolism · 2017 · 14 citations
    23. Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms Nature Communications · 2024 · 11 citations
    24. Glucose and acetate metabolism by isolated sheep wool follicles Archives of biochemistry and biophysics · 1965 · 8 citations
    25. The mechanotransducer Piezo1 coordinates metabolism and inflammation to promote skin growth Nature Communications · 2025 · 7 citations
    26. Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation Scientific reports · 2020 · 6 citations
    27. Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition Frontiers in molecular biosciences · 2022 · 4 citations
    28. Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling Pharmaceutics · 2022 · 2 citations
    29. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026
    30. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism eLife · 2026