Don’t Get Too Hyped About PP405. We've Seen This Movie Before.
    Research/Science 6/18/2025

    At a glance
    In this general discussion post the tone is skeptical.

    Other terms

    PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
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      community Switch from fin to dut and its worse

      in Finasteride/Dutasteride  2 upvotes 1 month ago
      Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.

      community July 1st - Early H2 - Breezula

      in Treatment 1 week ago
      Discussion on hair loss treatments, focusing on Breezula, with mentions of Minoxidil, finasteride, RU58841, Pyrilutamide, GT20029, and PP405. Breezula's effectiveness is uncertain, with some trials showing minimal regrowth.

      community What do you think about pyrilutamide?

      in Product  5 upvotes 5 months ago
      Pyrilutamide is being discussed as a potential hair loss treatment, but opinions are mixed, with some users skeptical about its effectiveness and the company's credibility. Some users report combining pyrilutamide with other treatments like dutasteride and microneedling, noting improvements, while others remain doubtful.

      community PP405 Phase 2a press release with early results

      in Research/Science  688 upvotes 3 weeks ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

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