Don’t Get Too Hyped About PP405. We've Seen This Movie Before.
    6/18/2025

    From the encyclopedia
    PP405 →

    mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

    Pyrilutamide →

    Experimental topical anti-androgen, also known as KX-826

    RU58841 →

    Experimental topical anti-androgen sold as a research chemical

    At a glance
    In this general discussion post the tone is skeptical.

    Other terms

    PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
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