Prevalence of Hormonal and Endocrine Dysfunction in Patients with Lichen Planopilaris: A Retrospective Data Analysis of 168 Patients

February 2017 in “ Journal of the American Academy of Dermatology ”

Geraldine Cheyana Ranasinghe, Melissa Piliang, Wilma F. Bergfeld

lichen planopilaris LPP hormonal imbalances endocrine dysfunctions pathogenesis

TLDR Lichen planopilaris (LPP) is linked to androgen excess, while frontal fibrosing alopecia (FFA) is linked to androgen deficiency.

The study titled "Prevalence of hormonal and endocrine dysfunction in patients with lichen planopilaris (LPP): A retrospective data analysis of 168 patients" analyzed the medical records of 168 individuals diagnosed with LPP to determine the prevalence of hormonal and endocrine dysfunctions. The findings indicated a significant association between LPP and various hormonal imbalances, suggesting that endocrine dysfunctions might play a role in the pathogenesis of LPP. This retrospective analysis provided valuable insights into the potential underlying mechanisms of LPP, highlighting the importance of considering hormonal evaluations in patients with this condition.

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