Frontal Fibrosing Alopecia: A Review of 60 Cases

    April 2012 in “ Journal of The American Academy of Dermatology ”
    Alison MacDonald, Colin Clark, Susan Holmes
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    TLDR Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.
    The 2012 review of 60 cases of Frontal Fibrosing Alopecia (FFA) indicated that this condition is predominantly found in postmenopausal Caucasian women, with a mean age of 64 and an average disease duration of 3.4 years. FFA is characterized by a recession of the frontotemporal hairline with associated symptoms such as eyebrow loss in 73% of patients, eyelash loss in 3%, and body hair loss in 25%. The study suggested that FFA might be linked to higher affluence and lower smoking rates, with 30% of patients having autoimmune diseases. Treatments like topical steroids and anti-inflammatory medications have shown limited success in stopping the progression of hair loss. FFA is considered a variant of lichen planopilaris, but its exact cause remains unknown, and there is a need for multicenter randomized controlled trials for effective management.
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