Acute Hair Loss on the Limbs in Frontal Fibrosing Alopecia: A Clinicopathological Study of Two Cases

    April 2010 in “ British journal of dermatology/British journal of dermatology, Supplement ”
    Mariya Miteva, Ivan D. Camacho, Paolo Romanelli, Antonella Tosti
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    TLDR Frontal fibrosing alopecia can cause sudden hair loss on limbs, similar to scalp hair loss.
    The study reported two cases of frontal fibrosing alopecia (FFA) with acute hair loss on the limbs, a rare manifestation of this condition. One case involved a 25-year-old premenopausal woman who initially experienced eyebrow thinning and frontal hairline recession, followed by abrupt patchy hair loss on her limbs. Histopathological examination of limb biopsies revealed features similar to scalp alopecia, including a single small vellus hair follicle with concentric fibroplasia and lymphocytic infiltrate. This study highlighted that limb involvement in FFA, though uncommon, shares histological characteristics with scalp involvement, suggesting a similar underlying pathological process.
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