Of PCOS Symptoms, Hirsutism Has the Most Significant Impact on the Quality of Life of Iranian Women

    April 2015 in “ PLOS ONE
    Mahnaz Bahri Khomami, Fahimeh Ramezani Tehrani, Somayeh Hashemi, Maryam Farahmand, Fereidoun Azizi
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    TLDR Excessive hair growth affects the quality of life of Iranian women with PCOS the most.
    In 2015, a study was conducted on 796 Iranian women aged 15-49 years diagnosed with polycystic ovary syndrome (PCOS). The study found that hirsutism, or excessive hair growth, had the most significant impact on their health-related quality of life. Other PCOS symptoms such as obesity, irregular menses, and infertility also affected their quality of life, but hirsutism was the most impactful. The study also found that the severity of hirsutism was directly proportional to the decrease in health-related quality of life score. The study concluded that healthcare officials should consider each clinical feature of PCOS separately when designing management strategies due to their varying impacts on psychological and physical health.
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      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 3 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

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      community Does low HGH leading to hairloss?

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      The user experiencing diffuse hair loss is using various treatments including RU58841, finasteride, minoxidil with tretinoin, anti-hair loss shampoo, and microneedling, and is considering adding peptides TB500, BPC157, and GHK-Cu. They have low growth hormone levels and are questioning its impact on hair loss, while another user suggests androgenic alopecia and androgens are likely the main cause of hair loss.

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