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Glossary Infertility

inability to conceive after one year of unprotected intercourse

Infertility, also known as sterility or reproductive failure, is the inability to conceive a child after one year of regular, unprotected sexual intercourse. It can result from issues in either partner, including hormonal imbalances, structural problems in the reproductive organs, or underlying health conditions.

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Research

5 / 1000+ results

research Infertility in Polycystic Ovary Syndrome: Focus on Low-Dose Gonadotropin Treatment

74 citations , January 2006 in “Endocrine journal”

Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.

research Finasteride use in the male infertility population: effects on semen and hormone parameters

54 citations , September 2013 in “Fertility and Sterility”

This study found that discontinuing finasteride led to a significant increase in sperm counts for most men with reduced fertility, though hormone levels and other semen parameters remained unchanged.

research Finasteride-associated male infertility

38 citations , December 2010 in “Fertility and Sterility”

In this case report, a male patient's semen parameters improved after discontinuing a 1-mg dose of finasteride, suggesting that stopping the medication may benefit infertile men with previous sperm production issues.

research Polycystic ovary syndrome and infertility: an update

26 citations , July 2021 in “International journal of adolescent medicine and health”

This review covers various treatments for managing PCOS symptoms and infertility, noting that aromatase inhibitors may be as or more effective than clomiphene citrate for ovulation induction but reports no new clinical results.

research Infertility Treatment in Polycystic Ovary Syndrome: Lifestyle Interventions, Medications and Surgery

19 citations , October 2012 in “Frontiers of Hormone Research”

This article reviews treatment strategies for ovulation induction in women with PCOS seeking pregnancy, emphasizing lifestyle changes and pharmacological options, and reports no new clinical findings.

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community Dutasteride Infertility Debunked: Low T causes true infertility.

168 upvotes 1 year ago

Dutasteride and finasteride may temporarily affect semen quality but are unlikely to cause permanent infertility. The Kim et al. study is criticized for poor methodology, and many prefer hair retention over potential fertility concerns, using treatments like dutasteride, finasteride, and minoxidil.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 1 year ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.

community Long-term use of dutasteride may lead to male infertility by persistently impairing semen volume and sperm motility.

in Finasteride/Dutasteride 87 upvotes 1 year ago

Long-term use of dutasteride may impair semen volume and sperm motility, but these effects are often reversible after stopping the drug. Individual reactions vary, and more research is needed to understand the long-term impact on fertility.

community Brief summary of new dutasteride study linked to infertility and the limitations/problems with the study

in Finasteride/Dutasteride 34 upvotes 1 year ago

Dutasteride treatment may decrease sperm concentration, but levels remain above WHO recommendations and recover after discontinuation. The study has limitations, including small sample size and lack of pre-treatment sperm data, and does not assess other fertility factors.

community Got results - 26YO - Almost infertile on medication?

50 upvotes 2 weeks ago

A 26-year-old male is concerned about potential infertility after using finasteride and dutasteride for hair loss, considering stopping the medication to recover fertility. He is contemplating freezing sperm and possibly undergoing a vasectomy, while others suggest stopping the medication and consulting a doctor.

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