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GlossaryCryptorchidism

condition where a testicle doesn't descend into the scrotum

Cryptorchidism, also known as an undescended testicle, is a condition where one or both of the testes fail to move into the scrotum before birth. This can lead to complications such as infertility and an increased risk of testicular cancer if not corrected, typically through surgical intervention called orchiopexy.

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research Regional Variation in Androgen Receptor Expression and Biomechanical Properties May Contribute to Cryptorchidism Susceptibility in the LE/Orl Rat

5 citations , December 2018 in “Frontiers in Endocrinology”

research Sperm Aneuploidy in Infertile Male Patients: A Systematic Review of the Literature

26 citations , October 2014 in “Andrologia”

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

research A Japanese Case of Ichthyosis Follicularis with Atrichia and Photophobia Syndrome with an MBTPS2 Mutation

14 citations , December 2010 in “Journal of human genetics”

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

research Canine Sertoli Cell Tumor: Anti-Müllerian Hormone, Inhibin B, and Estrone Sulphate

April 2023 in “Clinical theriogenology”

The dog's skin condition improved after removing a tumor that was causing hormone imbalances.

research A Brazilian Case of IFAP Syndrome With Severe Congenital Ichthyosis and Limb Malformations Caused by a Rare Variant in MBTPS2

January 2023 in “Revista Paulista de Pediatria”

A Brazilian male with IFAP syndrome has a unique genetic variant causing his condition.

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community Finasteride and fertility. Personal report.

in Finasteride/Dutasteride 829 upvotes 9 months ago

Finasteride can affect sperm quality, but fertility usually returns after stopping it, as shown by a user who conceived four months after discontinuation. Some users successfully conceive while on finasteride, though some prefer to pause its use to minimize risks.