Hirsutism: A Clinico-Investigative Study

    January 2012 in “ International Journal of Trichology ”
    Sunny Chhabra, Ram Krishnan Gautam, Bindu Kulshreshtha, Akhila Prasad, Neera Sharma
    Image of study
    TLDR Most cases of excessive hair growth in women are caused by polycystic ovarian syndrome and are linked to higher free testosterone levels.
    In the 2012 study involving 40 patients, researchers found that hirsutism, excessive terminal hair growth in androgen-sensitive areas, was primarily caused by polycystic ovarian syndrome (PCOS), accounting for 70% of cases. The severity of hirsutism was positively correlated with free testosterone levels. Other clinical features associated with hirsutism included acne, menstrual irregularities, acanthosis nigricans, obesity, and androgenetic alopecia. The study also indicated that idiopathic hirsutism might be over-diagnosed and emphasized the importance of thorough investigation to identify underlying causes for effective treatment. Significant hormonal differences were observed between hirsute patients and the control group, particularly in free testosterone, which was significantly associated with the severity of hirsutism.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 25 results

      community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.

      in Female  53 upvotes 1 year ago
      A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

      community How does hair loss and recovery work?

      in Chat  12 upvotes 3 months ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community AA and Hirsutism but T levels are normal

      in Female  8 upvotes 3 years ago
      27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

      community Finasteride 5mg & Spironolactone 100mg

      in Female  2 upvotes 3 weeks ago
      A 20-year-old female is using finasteride 5mg and spironolactone 100mg for severe hirsutism and is experiencing minor side effects like water weight loss and irregular periods. She is concerned about potential future side effects and hair regrowth on her scalp.

      community No, Finasteride as a treatment for MPB was not an "accident"

      in Research/Science  105 upvotes 3 years ago
      Finasteride was intentionally developed to treat BPH and later approved for male pattern baldness (MPB) due to its 5AR inhibition effects. The delay in MPB approval was due to concerns about off-label use for female hirsutism and the prioritization of treating a more debilitating condition.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  118 upvotes 3 months ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

    Related Research

    1 / 1 results