Endocrine Evaluation of Hirsutism

    June 2015 in “ International Journal of Women's Dermatology ”
    John Mihailidis, Racha Dermesropian, Pamela Taxel, Pooja Luthra, Jane M. Grant‐Kels
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    TLDR Hirsutism, excessive hair growth in women, is often caused by PCOS and can be managed with medication and personalized treatment plans.
    The 2015 article on hirsutism, a condition of excessive male-pattern hair growth in women, highlights that it affects 5 to 10% of women of reproductive age and is often linked to androgen excess, with PCOS being the most common cause. The article underscores the modest correlation between androgen levels and hair growth and suggests a comprehensive approach to diagnosis, including history, physical examination, and biochemical evaluation, especially for moderate to severe cases. Treatment options discussed include oral contraceptives like cyproterone acetate, which showed a 35% median decline in FG score, and antiandrogen therapies such as spironolactone, finasteride, and flutamide, which are effective but must be used cautiously due to side effects. Metformin and nonpharmacologic treatments are also mentioned as part of a patient-centered management plan that addresses both the physical and psychological aspects of hirsutism.
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