Comparison of Cyproterone Acetate Plus Ethinyl Estradiol and Finasteride in the Treatment of Hirsutism

    June 1998 in “ Journal of Endocrinological Investigation ”
    Yusuf Şahin, Fahri Bayram, Fahrettin Kelestimur, Iptisam Ipek Muderris
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    TLDR Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
    The document is a compilation of references related to the treatment of hirsutism. Several studies compared the effectiveness of two treatments, cyproterone acetate plus ethinyl estradiol and finasteride, in reducing hirsutism scores and androgen levels. Both treatments were found to be effective, but cyproterone acetate plus ethinyl estradiol was generally more effective in reducing hirsutism scores and androgen levels. However, both treatments had potential side effects and individual patient characteristics should be considered when choosing a treatment. One study found that finasteride may be a good alternative for treating hirsutism. Another study found that cyproterone acetate plus ethinyl estradiol was more effective and cost-effective than finasteride.
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