Pharmacology and Potential Use of Cyproterone Acetate

January 1977 in “ Hormone and metabolic research ”

F. Neumann

cyproterone acetate anti-androgen androgenic alopecia androgen receptors androgen production hirsutism severe acne

TLDR Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.

The document discussed the pharmacology and potential use of Cyproterone Acetate, a synthetic steroidal anti-androgen. It highlighted its effectiveness in treating conditions related to androgen excess, such as severe acne, hirsutism, and androgenic alopecia. The paper also covered its mechanism of action, which involves blocking androgen receptors and reducing androgen production. Additionally, the document mentioned its use in prostate cancer therapy and as a component of hormone therapy for transgender women. The findings were based on clinical observations and trials conducted up to 1975.

View this study on thieme-connect.de →

Discuss this study in the Community →

Similar Research

6 / 1000+ results

research Androgens and Androgen Receptor in the Management of Skin Diseases

1 citations, January 2022 in “Journal of Biosciences and Medicines”

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

research Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

November 2020 in “Elsevier eBooks”

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

research Hormonal Therapy for Acne: Why Not as First Line Therapy? Facts and Controversies

76 citations, December 2009 in “Clinics in Dermatology”

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

research Interventions for Female Pattern Hair Loss

35 citations, May 2012 in “Cochrane Database of Systematic Reviews”

Minoxidil effectively treats female pattern hair loss.

research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow

70 citations, February 2015 in “Expert Opinion on Drug Discovery”

Topical drugs and near-infrared light therapy show potential for treating alopecia.

research Androgenetic Alopecia: An Autosomal Dominant Disorder

80 citations, January 1995 in “The American Journal of Medicine”

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Pharmacology and Potential Use of Cyproterone Acetate

Related Community Posts Join

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

community It’s over. NOTHING has worked.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

community Are these all the anti androgen products?

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.