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    Glossary Immune Privilege

    certain body areas limit immune responses to prevent tissue damage

    Immune privilege refers to certain areas of the body, such as the eyes, brain, and hair follicles, where the immune system's activity is naturally limited to prevent damage to delicate tissues. This means that these areas can tolerate the introduction of antigens without eliciting a strong inflammatory immune response, which helps protect critical functions but can also make them vulnerable to infections or diseases.

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    Research 10 of 1000+

    1. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007 · 253 citations
    2. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    3. Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege Journal of Investigative Dermatology · 2005 · 139 citations
    4. Hair follicle immune privilege and its collapse in alopecia areata Experimental dermatology · 2020 · 134 citations
    5. Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management 2017 · 102 citations
    6. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    7. Immune Privilege Collapse and Alopecia Development: Is Stress a Factor Skin Appendage Disorders · 2017 · 51 citations
    8. Does collapse of immune privilege in the hair-follicle bulge play a role in the pathogenesis of primary cicatricial alopecia? Clinical and Experimental Dermatology · 2009 · 39 citations
    9. Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse 2016 · 36 citations
    10. Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege 2013 · 27 citations
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    Community 2 of 10

    1. If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied Community · 8 Aug 2024
    2. Telogen Effluvium/Chronic TE and immune-related hair loss advice Reddit · 8 Aug 2018
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