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    Glossary Immune Tolerance

    process where immune system avoids attacking body's own cells

    Immune tolerance is the process by which the immune system learns to recognize and not attack the body's own cells and tissues. This is crucial for preventing autoimmune diseases, where the immune system mistakenly targets the body's own cells, such as in alopecia areata where hair follicles are attacked. For professionals, it involves mechanisms like central tolerance in the thymus and peripheral tolerance in other tissues to maintain self-tolerance and prevent autoimmunity.

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    1. Ex Vivo Treatment with Allogenic Mesenchymal Stem Cells of a Healthy Donor on Peripheral Blood Mononuclear Cells of Patients with Severe Alopecia Areata: Targeting Dysregulated T Cells and the Acquisition of Immunotolerance International Journal of Molecular Sciences · 2022 · 1 citations
    2. IL-15 in alopecia areata: the immune tolerance mechanistic insights and translational perspectives Frontiers in Medicine · 2026
    3. Hair follicle immune privilege in autoimmune and immune-mediated alopecias: paths toward reestablishing immune tolerance Frontiers in Medicine · 2026
    4. Nanoparticle Adjuvants Incorporating Haptens Drive Potent Immune Tolerance to Accelerate Hair Regrowth ACS Applied Materials & Interfaces · 2025
    5. Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease 2018 · 26 citations
    6. Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis Frontiers in Science · 2026 · 2 citations
    7. Regulation of immune response genes in the skin of allergic and clinically tolerant individuals exposed to p‐phenylenediamine Allergy · 2024 · 4 citations
    8. Internal peacekeepers and external mediators: A new model of peripheral immune tolerance involving regulatory T cells and mesenchymal stem cells Advances in Clinical and Experimental Medicine · 2026
    9. Regulatory T cells in dominant immunologic tolerance Journal of Allergy and Clinical Immunology · 2023 · 26 citations
    10. Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche Science Immunology · 2024 · 21 citations
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    1. Telogen Effluvium/Chronic TE and immune-related hair loss advice Reddit · 8 Aug 2018
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