Search
for

    Glossary Cytotoxic T-Lymphocyte Antigen 4

    regulates immune response by inhibiting T cell activation

    Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) is a protein found on the surface of T cells, which are a type of immune cell. It acts as an "off switch" to help regulate the immune system by preventing it from attacking the body's own tissues. This protein is crucial in maintaining immune tolerance and preventing autoimmune diseases.

    Related Terms

    Research 10 of 1000+

    1. Studying Cytotoxic T-lymphocyte- Associated Antigen-4 (CTLA-4) gene Polymorphism in a Sample of Iraqi Women with Polycystic Ovarian Syndrome Al-ʻulūm al-ṣaydalāniyyaẗ · 2019 · 2 citations
    2. Studying Cytotoxic T-lymphocyte- Associated Antigen-4 (CTLA-4) gene Polymorphism in a Sample of Iraqi Women with Polycystic Ovarian Syndrome Al Mustansiriyah Journal of Pharmaceutical Sciences · 2019
    3. Type 1 interferon signature and cytotoxic T lymphocyte activation targeted against sweat ducts in inflammatory acquired idiopathic generalized anhidrosis Journal of the European Academy of Dermatology and Venereology · 2023 · 6 citations
    4. Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions F1000Research · 2015 · 15 citations
    5. Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition Nature medicine · 2014 · 701 citations
    6. Clinicopathological Features and Pathogenesis of Thymoma Complicated with Alopecia Areata: A Multicenter, Matched Case Analysis Cancers · 2025
    7. Meta-Analysis of Gene Expression Reveals the Core Transcriptomic Profile of Lesional Scalp in Alopecia Areata Dermatology and Therapy · 2025
    8. Innate lymphoid cells type 1 may be new, non-antigen-specific player in the pathogenesis of alopecia areata 2019
    9. Pathophysiology of the Behçet's Disease Pathology Research International · 2011 · 34 citations
    10. Etiology of cicatricial alopecias: a basic science point of view Dermatologic therapy · 2008 · 35 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →