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    Did you mean CD4+ T cells?
    Glossary CD4+ T cells

    specialized white blood cells that coordinate immune responses

    CD4+ T cells, also known as T helper cells, are a type of white blood cell that plays a crucial role in the immune system. They help coordinate the body's response to infections by signaling other immune cells, such as B cells and cytotoxic T cells, to perform their functions. These cells are essential for mounting an effective immune response and are notably targeted by HIV, which can lead to a weakened immune system.

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    1. Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation Nature communications · 2016 · 155 citations
    2. Transient CD44 Variant Isoform Expression and Reduction in CD4+/CD25+ Regulatory T Cells in C3H/HeJ Mice with Alopecia Areata Journal of Investigative Dermatology · 2002 · 77 citations
    3. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    4. CD80CD86 deficiency disrupts regulatory CD4+FoxP3+T cell homoeostasis and induces autoimmune-like alopecia Experimental dermatology · 2017 · 6 citations
    5. CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease The Journal of Immunology · 2023 · 1 citations
    6. Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1 Frontiers in Pharmacology · 2022 · 1 citations
    7. Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata 2025
    8. 035 Expansion of bacterial phosphatidylglycerol reactive CD4+ T cells in atopic dermatitis Journal of Investigative Dermatology · 2021
    9. 0036 IL-27 generates immunosuppressive CD4 T cells and and prevents the development of alopecia areata Journal of Investigative Dermatology · 2025 · 1 citations
    10. T <sub>H</sub> 1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata Science Advances · 2025
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