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GlossaryCytotoxic Drugs

medications that kill or inhibit rapidly dividing cells

Cytotoxic drugs, also known as chemotherapeutic agents, are medications designed to kill or inhibit the growth of rapidly dividing cells, such as cancer cells. While effective in treating various cancers, these drugs can also affect healthy cells that divide quickly, like those in hair follicles, leading to side effects such as hair loss (alopecia).

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Atrophic Telogen Effluvium from Cytotoxic Drugs and a Randomized Controlled Trial to Investigate the Possible Protective Effect of Pretreatment with a Topical Vitamin D3 Analogue in Humans

research Atrophic Telogen Effluvium from Cytotoxic Drugs and a Randomized Controlled Trial to Investigate the Possible Protective Effect of Pretreatment with a Topical Vitamin D3 Analogue in Humans

47 citations , July 2005 in “British Journal of Dermatology”

Topical vitamin D3 does not prevent hair loss from chemotherapy.

research Host-Directed FDA-Approved Drugs with Antiviral Activity Against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods

42 citations , April 2021 in “Pharmaceuticals”

Five FDA-approved drugs may help block COVID-19 virus entry.

research The Control of Hair Growth

34 citations , October 1998 in “PubMed”

Future drugs targeting specific hair growth steps could improve treatments for hair growth issues.

research The Pregnant Urologist: Occupational Risks and Safety Measures

5 citations , June 2017 in “BJU international”

Pregnant female urologists should avoid certain drugs and use protective measures to stay safe.

research Cutaneous Drug Reactions

1 citations , January 2010 in “Elsevier eBooks”

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 59 upvotes 2 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community This, and the UCLA molecule(linked article in comments)…I have great hopes

in Research/Science 203 upvotes 2 months ago

Oleic acid and ethanol are being considered for hair regrowth, with some users planning to self-experiment. There is skepticism about their effectiveness, and ongoing use of treatments like finasteride and minoxidil is mentioned.

community It's always the Mice that gets to grow back hair.

in Research/Science 431 upvotes 2 months ago

Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 9 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

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