Cutaneous Drug Reactions

January 2010 in “ Elsevier eBooks ”

David Weedon

Studysummary Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

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Research cited in this study

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research An Unusual Terminal Hair Growth on the Nose Tip Associated with Gefitinib Therapy

4 citations , March 2007 in “British Journal of Dermatology”

This case report observed that terminal hair growth on the nose tip was associated with gefitinib treatment in a 65-year-old woman with lung adenocarcinoma.

research Cutaneous Necrosis After Injection of Polyethylene Glycol–Modified Interferon Alfa

26 citations , June 2005 in “Journal of The American Academy of Dermatology”

In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.

research Psychoactive Drugs and Skin

12 citations , June 2003 in “Journal of the European Academy of Dermatology and Venereology”

This review discusses the range and management of adverse cutaneous reactions to psychotropic medications and emphasizes the need for awareness among clinicians, concluding with a call for careful monitoring and patient education.

research Pseudoacromegaly Induced by the Long-Term Use of Minoxidil

41 citations , June 2003 in “Journal of The American Academy of Dermatology”

This case report describes a patient who developed pseudoacromegaly from long-term use of high-dose minoxidil, marking the first such documented case.

research Mucocutaneous Reactions to Chemotherapy

275 citations , March 1999 in “Journal of The American Academy of Dermatology”

This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.

research Cutaneous Reactions to Recombinant Cytokine Therapy

105 citations , September 1995 in “Journal of The American Academy of Dermatology”

This review discusses the use of recombinant cytokines as therapeutic agents in clinical settings and describes the range of cutaneous complications associated with their use, including both minor and severe skin reactions.