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    GlossaryToxic Epidermal Necrolysis

    severe skin reaction causing widespread cell death and skin detachment

    Toxic Epidermal Necrolysis (TEN) is a rare, life-threatening skin condition characterized by widespread skin cell death, leading to the detachment of the epidermis from the underlying dermis. Often triggered by a severe reaction to medications, it presents with symptoms similar to severe burns, including extensive blistering and peeling of the skin, and requires immediate medical attention.

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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Do you keep gains if you stop microneedling?

      in Microneedling  15 upvotes 7 months ago
      Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community People who don’t microneedle, why?

      in Microneedling  146 upvotes 5 months ago
      Microneedling is often combined with minoxidil for hair growth, but concerns about scalp damage, pain, and effectiveness deter some users. Alternatives like finasteride, dutasteride, tretinoin, and laser treatments are preferred by others.