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    Glossary Toxic Epidermal Necrolysis

    severe skin reaction causing widespread cell death and skin detachment

    Toxic Epidermal Necrolysis (TEN) is a rare, life-threatening skin condition characterized by widespread skin cell death, leading to the detachment of the epidermis from the underlying dermis. Often triggered by a severe reaction to medications, it presents with symptoms similar to severe burns, including extensive blistering and peeling of the skin, and requires immediate medical attention.

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    1. Long-term complications of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN): the spectrum of chronic problems in patients who survive an episode of SJS/TEN necessitates multidisciplinary follow-up British Journal of Dermatology · 2017 · 105 citations
    2. Toxic Epidermal Necrolysis Medical Clinics of North America · 1980 · 74 citations
    3. TOXIC EPIDERMAL NECROLYSIS International Journal of Dermatology · 1992 · 48 citations
    4. Fatal Toxic Epidermal Necrolysis Associated With Cetuximab in a Patient With Colon Cancer Journal of Clinical Oncology · 2008 · 35 citations
    5. Severe Physical Complications among Survivors of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Drug Safety · 2017 · 33 citations
    6. Toxic epidermal necrolysis due to cephalexin Journal of The American Academy of Dermatology · 1987 · 14 citations
    7. Fatal Toxic Epidermal Necrolysis Associated with Minoxidil Pharmacotherapy · 2009 · 11 citations
    8. Toxic epidermal necrolysis caused by skin hypersensitivity to monosulfiram. The BMJ · 1968 · 9 citations
    9. Ocular and Mucocutaneous Sequelae among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo Dermatology Research and Practice · 2019 · 6 citations
    10. A case of eruptive lichen spinulosus after toxic epidermal necrolysis Pediatric dermatology · 2022 · 1 citations
    11. Toxic epidermal necrolysis caused by etonogestrel implantation: A rare presentation JAAD case reports · 2022 · 1 citations
    12. Amiodarone-Induced Toxic Epidermal Necrolysis; Nilotinib-Associated Cerebrovascular Disease and Stroke; Pisa Syndrome Caused by Paliperidone; Macroglossia Associated with Methylprednisolone; Aromatase Inhibitor-Induced “Male Pattern Baldness” in Women? Acute Liver Failure Due to Etodolac Hospital Pharmacy · 2013
    13. The chronic phase of Stevens-Johnson syndrome and toxic epidermal necrolysis: beyond skin and eyes The Sri Lanka Journal of Dermatology · 2025
    14. Fatal Case of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Induced by Doxycycline or Flucloxacillin in a 77-Year-Old Woman: A Rare but Serious Adverse Drug Reaction Cureus · 2025
    15. LB1009 Baicalin, a component of the herbal medicine Baikal skullcap, inhibits epidermal necroptosis in SJS/TEN Journal of Investigative Dermatology · 2024
    16. TATA LAKSANA TERKINI PENYAKIT SINDROM STEVENS-JOHNSON (SSJ)/ NEKROLISIS EPIDERMAL TOKSIK (NET) Media Dermato Venereologica Indonesiana · 2023
    17. Severe cutaneous adverse reactions to drugs The Lancet · 2017 · 273 citations
    18. Drug-Induced Skin, Nail and Hair Disorders Drug Safety · 2007 · 114 citations
    19. Identification of drug-specific public TCR driving severe cutaneous adverse reactions Nature communications · 2019 · 88 citations
    20. Cutaneous effects of the most commonly used antidepressant medication, the selective serotonin reuptake inhibitors Journal of The American Academy of Dermatology · 2006 · 55 citations
    21. Induction of De Novo Hair Regeneration in Scars After Fractionated Carbon Dioxide Laser Therapy in Three Patients Dermatologic Surgery · 2011 · 20 citations
    22. Anticonvulsant-Induced Cutaneous Reactions CNS Drugs · 1999 · 18 citations
    23. Spontaneous cutaneous adverse drug reaction reports—An analysis of a 10‐year dataset in Singapore Pharmacology Research & Perspectives · 2019 · 13 citations
    24. Séquelles cutanéomuqueuses et oculaires des SJS et de Lyell Annales de Dermatologie et de Vénéréologie · 2010 · 13 citations
    25. Psychoactive drugs and skin Journal of the European Academy of Dermatology and Venereology · 2003 · 12 citations
    26. Drug eruptions in dermatology Expert Review of Dermatology · 2011 · 11 citations
    27. Cutaneous toxicities of new targeted cancer therapies: must know for diagnosis, management, and patient-proxy empowerment Annals of palliative medicine · 2019 · 7 citations
    28. Adverse cutaneous effects of psychotropic medications Expert Review of Dermatology · 2013 · 6 citations
    29. Dermatologic Conditions of the Early Post-Transplant Period in Hematopoietic Stem Cell Transplant Recipients American Journal of Clinical Dermatology · 2018 · 5 citations
    30. Cutaneous Reactions to Drugs Elsevier eBooks · 2017 · 3 citations