A Case of Eruptive Lichen Spinulosus After Toxic Epidermal Necrolysis

December 2022 in “ Pediatric dermatology ”

Celine Phong, Suzanne W Birmingham, Bonnie A Lee, Nathan W. Rojek

lichen spinulosus toxic epidermal necrolysis lamotrigine amoxicillin follicular papules atopy ammonium lactate TEN LS

TLDR A boy developed a rare skin condition after recovering from a severe skin reaction, and it improved with lotion treatment.

A 13-year-old boy with a history of attention-deficit/hyperactivity disorder and epilepsy developed lichen spinulosus (LS), a rare skin condition, after recovering from toxic epidermal necrolysis (TEN), a severe skin reaction. The boy had been hospitalized for TEN, which covered 80% of his body and was possibly caused by lamotrigine or amoxicillin. After his skin healed, he developed white papules on his trunk and arms, which were diagnosed as LS. LS is characterized by patches of follicular papules and is typically seen in pediatric/adolescent patients. The cause of LS is not well understood, but it has been associated with atopy, infections, genetics, and drug reactions. The boy was treated with ammonium lactate 12% lotion daily and reported improvement in his pruritus at a 2-week follow-up. This is the first reported case of LS following TEN.

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