Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions

    August 2019 in “ Nature communications ”
    Ren‐You Pan, Mu-Tzu Chu, Chuang‐Wei Wang … Shuen‐Iu Hung
    Studysummary In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.
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