Dutasteride: More Than a DHT Reducer – A Potential Androgen Receptor Inhibitor? Finasteride/Dutasteride 12/20/2024
Dutasteride may inhibit androgen receptors in addition to reducing DHT, potentially explaining its effectiveness over finasteride for hair loss. Concerns about its impact on muscle growth are debated, with some suggesting no significant effects.
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6 / 1000+ resultscommunity Dutasteride/finasteride theory
Finasteride worked better for frontal scalp hair loss, while dutasteride helped the crown and mid-scalp but worsened the frontal area. The user shared personal experiences and invited open dialogue.
community Can aromatase inhibitors make dutasteride/finasteride useless?
The conversation discusses using aromatase inhibitors with dutasteride or finasteride for hair loss, which can prevent testosterone from turning into estrogen but may lead to increased DHT and potentially make finasteride less effective. There's concern about proper dosing and side effects like gynecomastia and emotional changes.
community How To Switch from Finasteride to Dutasteride (according to literature)
Switching from finasteride to dutasteride for hair loss treatment. Dutasteride is suggested as a more effective alternative.
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A user shared a 10-month hair loss treatment update using oral dutasteride, topical minoxidil, topical finasteride, microneedling, biotin, and saw palmetto. Replies praised the progress and suggested additional treatments like tretinoin and RU58841.
community Why does finasteride stop working?
Finasteride may seem less effective over time due to increased DHT sensitivity or aging, but it still suppresses DHT. Switching to dutasteride offers stronger DHT suppression but may increase estrogen levels.
community RU58841 alone vs. with Fin / Dut
RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.
Related Research
6 / 1000+ resultsresearch Dutasteride/Finasteride
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Man experienced post-finasteride syndrome symptoms after using finasteride and dutasteride for hair loss.
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Dutasteride more effective for hair growth, but has more side effects than finasteride.
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Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.