Understanding, Recognizing, and Managing Toxicities of Targeted Anticancer Therapies

    May 2013 in “ Ca ”
    Grace K. Dy, Alex A. Adjei
    Studysummary This review discusses the shift in toxicity profiles of cancer therapies from traditional chemotherapy to targeted agents, noting similar overall toxicities but with different side effects, and reports no new findings.
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    Research cited in this study 3

    1. Hair Depigmentation Is a Biological Readout for Pharmacological Inhibition of KIT in Mice and Humans Journal of Pharmacology and Experimental Therapeutics · 2003
    2. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001
    3. Expression of a Dominant Negative Mutant of Epidermal Growth Factor Receptor in the Epidermis of Transgenic Mice Elicits Striking Alterations in Hair Follicle Development and Skin Structure. The EMBO Journal · 1995