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    Glossary Steroids

    Steroids are synthetic substances that mimic the effects of hormones like testosterone in the body. They are often used in medical treatments but can also lead to hair loss as a side effect, particularly when they disrupt the natural hormonal balance. In the context of hair biology, anabolic steroids can cause androgenic alopecia, a condition characterized by thinning hair and baldness, especially in genetically predisposed individuals. Key distinguishing characteristics include their potential to increase hair loss in both men and women, depending on individual sensitivity to androgens.

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    Research 10 of 1000+

    1. Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition Endocrine Reviews · 2005 · 451 citations
    2. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    3. Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1) Journal of Investigative Dermatology · 2003 · 289 citations
    4. GhDET2, a steroid 5α‐reductase, plays an important role in cotton fiber cell initiation and elongation The Plant Journal · 2007 · 193 citations
    5. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor Journal of the American Chemical Society · 1996 · 136 citations
    6. LC‐MS/MS‐based method for long‐term steroid profiling in human scalp hair Clinical Endocrinology · 2015 · 134 citations
    7. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    8. Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne Cochrane library · 2009 · 112 citations
    9. Steroid sulfatase inhibitors Medicinal Research Reviews · 2004 · 108 citations
    10. Systemic Steroids With or Without 2% Topical Minoxidil in the Treatment of Alopecia Areata Archives of Dermatology · 1992 · 101 citations
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    Community 10 of 87

    1. 20yo Considering Dutasteride vs Finasteride During Steroid Cycle Risks Community · 13 Jun 2026
    2. My hair after 3 steroid cycles Reddit · 27 Jun 2024
    3. Dutasteride vs Finasteride and Steroid Reddit · 3 Oct 2025
    4. How. can I counteract the rapid hair loss caused by steroids? Reddit · 6 Feb 2025
    5. Ru-58841 vs KX-826/pyrilutamide while on steroids Reddit · 29 Oct 2024
    6. Does it matter if I introduce steroids while my RU58841 shed is still active, or should I wait until it settles? Reddit · 27 Aug 2026
    7. Ru58841 + primobolan or masteron as a way to protect hair while on steroids Reddit · 27 Feb 2026
    8. If you discontinued anabolic steroids (mainly Testosterone) while on Dut, would you restart seeing results? Reddit · 13 Jul 2026
    9. I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation? Reddit · 23 Jun 2025
    10. Finasteride does deplete important nuero-active steroids Reddit · 9 Aug 2023
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