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    Glossary Immune Dysregulation

    malfunctioning immune system attacking body's own tissues

    Immune dysregulation refers to an imbalance or malfunction in the immune system, where it either overreacts, underreacts, or attacks the body's own tissues. This can lead to various health issues, including autoimmune diseases like alopecia areata, where the immune system mistakenly targets hair follicles, causing hair loss.

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    1. Immune Dysregulation in Chronic Inflammatory Skin Disorders: An Integrative Immunopathological Review IECCMEXICO · 2026
    2. Rapidly Progressive Alopecia Universalis after Varicella-Zoster Virus Infection: The role of Immune Dysregulation and Tofacitinib treatment 2025
    3. Proteomic Profiling of Central Centrifugal Cicatricial Alopecia Reveals Role of Humoral Immune Response Pathway and Metabolic Dysregulation JID Innovations · 2024 · 5 citations
    4. Environmental Modulation of JAK3-Mediated Immune Dysregulation in Alopecia Areata Scholarly Commons (Embry–Riddle Aeronautical University) · 2025
    5. Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome Research Square (Research Square) · 2023
    6. A Case Study on Exploring Immune Dysregulation in Alopecia Areata - Mechanisms and Treatments Outcomes International Journal of Pharmaceutical Sciences Review and Research · 2025
    7. Baricitinib-Induced Remission of Alopecia Universalis in a Child with NFKB2-Associated Immune Dysregulation Journal of Clinical Immunology · 2025 · 2 citations
    8. Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease‐associated psychological morbidity 2019 · 57 citations
    9. Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction? Experimental dermatology · 2021 · 9 citations
    10. Early prediction of alopecia areata using machine learning modeling of neuro stress immune signatures from multi datasets Scientific Reports · 2025 · 1 citations
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    Community 1 of 10

    1. Telogen Effluvium/Chronic TE and immune-related hair loss advice Reddit · 8 Aug 2018
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