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    GlossaryImmune Dysregulation

    malfunctioning immune system attacking body's own tissues

    Immune dysregulation refers to an imbalance or malfunction in the immune system, where it either overreacts, underreacts, or attacks the body's own tissues. This can lead to various health issues, including autoimmune diseases like alopecia areata, where the immune system mistakenly targets hair follicles, causing hair loss.

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      learn Baricitinib

      JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

      learn Vitamin D

      vitamin you should probably be taking for general health might also help your hair a little

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

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      community Opinions on Scalp fibrosis and DHT?

      in Research/Science  9 upvotes 2 years ago
      The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

      community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

      in Progress Pictures  492 upvotes 2 years ago
      A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.